Chemical and Biological Effects of Some Mixtures of Plant Oils and Thymus vulgaris on liver Diseases

Abstract

The liver is a vital organ with a wide range of functions that can influence other body organs .Liver plays an important role in regulation of lipid in the body. Excess dietary fat and increased insulin glucose level will increase fatty acids in liver and there for triglycerides leading to its accumulation causing steatosis. The liver is highly susceptible to many diseases due to its significant role primarily in metabolism of fat, carbohydrates, and proteins. Liver disease is a common worldwide public health problem that may result from a variety of hepatic injuries. The most frequent form of liver disease is chronic hepatitis. Dietary components are essential for the healthy or diseased liver. Selected food plants can provide nutritional and medicinal support for liver diseases. Herbal and oil medicinal products are increasingly being used and many of them have shown promising potential for the treatment of liver diseases Considering the role of oxidative stress in pathogenesis of a wide range of liver diseases, natural antioxidant products, especially phytochemicals, are widely used in their treatment and nearly half of the agents used in liver therapy today are either natural products or their derivatives. The present study aimed to evaluate the chemical and biological effects of some mixtures of plant oils and Thymus vulgaris on carbon tetrachloride CCl4 induced changes in liver enzymes of albino rats, and evaluate the effect of mixture between oil and Thymus vulgaris with high and low doses on carbon tetrachloride-induced liver injury in experimental rats.