THREE-DIMENSIONAL FLUID STRUCTURE INTERACTION ANALYSIS OF ATHEROSCLEROTIC CAROTID ARTERY MODELS OF DIFFERENT CALCIFICATION PATTERNS

Abstract

We presented an image-based computational modelling analysis for atherosclerotic carotid artery models with different calcification patterns. We built various carotid models based on patient specific magnetic resonance images of atherosclerotic carotid artery for a symptomatic patient. 3D Fluid structure interaction computations were performed to study the mechanical behaviour of the atherosclerotic carotid models. We investigated the stress/strain analysis of carotid plaque models that encompassed different calcification patterns. We also studied the impact of plaque morphology, stenosis degree level, material properties on the mechanical behaviour of the carotid models. Predicting the mechanical behaviour of carotid plaques leads to better patient diagnosis, and treatment as well as decreasing the high risk for endovascular procedures.