Role of Contrast Enhanced Mammography in Diagnosis of Malignant Breast Lesion with Histopathological Correlation

Abstract

ontrast enhanced digital mammography (CEDM) is an advanced technique to detect the tumor neoangiogenesis by using two techniques either the temporal subtraction technique with acquisition of high-energy images before and after contrast medium injection or the dual energy technique with acquisition of a pair of low and high-energy images only after contrast medium injection. The potential clinical applications are the clarification of mammographically equivocal lesions, the detection of occult lesions on standard mammography, particularly in dense breast, the determination of the extent of disease, the assessment of recurrent disease and the monitoring of the response to chemotherapy. The purpose of this study was to evaluate the capability of CESM to diagnose the suspicious breast lesions, to assess the diagnostic performance of CESM in comparison to the conventional imaging and to suggest the most reliable morphology descriptors and enhancement criteria to differentiate benign and malignant lesions. 35 female patients with suspicious breast lesions, were enrolled in our study, age ranged from 27 to 79 years. All patients underwent conventional mammography and ultrasound then CESM.