Laser Ablation of Non-Muscle Invasive Bladder Tumors; Any Advantage Over Standard Resection Prospective Comparative Study

Abstract

The choice of treatment modality in patients with Non muscle invasive bladder cancer (NMIBC) is one of the most discussed issues in urology. One of major problems in management of NMIBC in high recurrence and progression rates. In recent years, the laser has increasing role in different urological fields. Aim of the Work: Evaluation of the value of adding LASER ablation of the tumor bed after resection of the non-muscle invasive transitional cell carcinoma of the urinary bladder. Patients and Methods: 136 patients with non-muscle invasive bladder cancer randomly divided into two groups: Group 1 underwent Laser ablation of tumor bed after resection (Laser group) (n=68), and Group 2 underwent conventional transurethral resection of bladder tumor (TURBT group) (n=68). Operation time, irrigation time, Catheterization time, postoperative hospital stay, Postoperative clot retention or any postoperative complications, and results after each follow up cystoscopy were collected and compared. Results: after one year follow up for all patients we found that patients who underwent laser ablation after resection has less recurrence or progression rates than patients of the other group which was significant statistically. Also they had less postoperative hospital stay and early catheter removal. Conclusion: laser found that it can decrease the recurrence and progression rates in NMIBC after 1 year follow up, it also found to improve postoperative hematuria and decrease postoperative catheterization time and postoperative hospital stay when compared to conventional TURBT.