¬Lactate Clearance versus Base Deficit Correction in Monotoring of Septic Shock

Abstract

epsis is a dysregulated host response to infection resulting in potentially life-threatening organ dysfunction. Early recognition of ICU patients in a greater risk of development of subsequent complications helps to decrease the burden of morbidity and mortality in those patients. The aim of this study was to assess the clinical utility of lactate clearance and arterial base deficit correction in predicting mortality in septic shock. This study included 40 patients who developed septic shock after admission into ICU, recruited from Ain Shams University Hospital, Cairo, Egypt. The patients were followed up along the study period and divided into 2 equal groups; each of 20 patients, Group I (non-survivor group): patients who were didn’t survive after development of sepsis and septic shock and group II (Survivor group): patients who patients who survived after development of sepsis and septic shock. All the included cases were subjected to full history taking and full general and local examination. Full laboratory investigations were taken from all the cases. GCS was calculated to assess the neurological state of the patients. Serum lactate and BD were calculated for all the cases.