(GATA-1 and GATA-2 gene Expression in Myelodysplastic Syndromes (MDS

ASMAA AHMED ABDEL AAL;

Abstract


GATA-l and GATA-2 are 2 transcription factors act co­ operatively during normal haematopoiesis. Our study aimed to detected their expression patterns in MDS and AAML. GATA-2 was detected in 69.6% of MDS cases, while GATA-1 was negative in all cases. In AML cases, GATA-I was expressed in
56% of cases and GATA-2 in 80% of cases. Our study suggests critical role of GATA-1 and GATA-2 in the development of MDS andAML.


Other data

Title (GATA-1 and GATA-2 gene Expression in Myelodysplastic Syndromes (MDS
Other Titles التعبير الجينى لجاتا 1 و جاتا 2 فى حالات متلازمة سوء النمو النخاعى
Authors ASMAA AHMED ABDEL AAL
Issue Date 2006

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