Antioxidant activity of some N-heterocycles derived from 2-(1-(2-oxo-2H-chromen-3-yl)ethylidene) hydrazinecarbothioamide
El-Helw, EAE; Sallam, H.A.; Elgubbi, AS;
Abstract
Efficient and convenient synthesis of coumarin derivatives was accomplished via reactions of 2-(1-(2-oxo-2H-chromen-3-yl)ethylidene)hydrazinecarbothioamide with some carbon electrophiles, e.g. maleic anhydride, dimethyl acetylenedicarboxylate, 1,2-dichloroethane, 3′-nitro-w-bromoacetophenone, N-(4-acetylphenyl)-2-chloroacetamide, ethyl cyanoacetate/3-chlorobenzaldehyde and acetylacetone to construct some N-heterocycles such as thiazolidine, thiazole, pyrimidine and pyrazolone derivatives. The structures of all synthesized products were substantiated from their analytical and spectral data. The antioxidant activities of the synthesized compounds were examined.
Other data
Title | Antioxidant activity of some N-heterocycles derived from 2-(1-(2-oxo-2H-chromen-3-yl)ethylidene) hydrazinecarbothioamide | Authors | El-Helw, EAE ; Sallam, H.A. ; Elgubbi, AS | Keywords | Antioxidant activity;coumarin;pyrimidine;thiosemicarbazone;thiazolidinone;BEARING | Issue Date | 2019 | Publisher | TAYLOR & FRANCIS INC | Journal | SYNTHETIC COMMUNICATIONS | Volume | 49 | Issue | 20 | Start page | 2651 | End page | 2661 | ISSN | 0039-7911 | DOI | 10.1080/00397911.2019.1638938 | Scopus ID | 2-s2.0-85070912313 | Web of science ID | WOS:000481435200004 |
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