Regenerative potential of cultured gingival fibroblasts in treatment of periodontal intrabony defects (randomized clinical and biochemical trial)
Abdal-Wahab, Mahetab; Abdel Ghaffar, Khaled A; Ezzatt, Ola; Hassan, Ahmed Abdel Aziz; El Ansary, Mervat Mohamed S; Gamal, Ahmed Y;
Abstract
Defective cellular elements constitute an important challenge to achieve predictable periodontal regeneration. In an attempt to improve the cellularity of periodontal defects, gingival fibroblasts were implanted without their associated extracellular elements in periodontal defects to expose them to periodontal tissue mediators. In order to investigate the regenerative potential of gingival fibroblasts translocated into periodontal defects, the present study was designed to clinically and biochemically investigate the use of gingival fibroblasts (GF) and their associated mesenchymal stem cells (GMSC) in the treatment of intrabony periodontal defects.
Other data
Title | Regenerative potential of cultured gingival fibroblasts in treatment of periodontal intrabony defects (randomized clinical and biochemical trial) | Authors | Abdal-Wahab, Mahetab; Abdel Ghaffar, Khaled A; Ezzatt, Ola ; Hassan, Ahmed Abdel Aziz; El Ansary, Mervat Mohamed S; Gamal, Ahmed Y | Keywords | gingival fibroblasts; gingival mesenchymal stem cells; intrabony pockets; periodontal regeneration | Issue Date | Jun-2020 | Publisher | WILEY | Journal | Journal of periodontal research | ISSN | 0022-3484 1600-0765 |
DOI | 10.1111/jre.12728 | PubMed ID | 32080858 | Scopus ID | 2-s2.0-85085234398 | Web of science ID | WOS:000535073200012 |
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