Circulating MiR-210 and MiR-1246 as Potential Biomarkers for Differentiating Hepatocellular Carcinoma from Metastatic Tumors in the Liver

Ahmed, Emad, Fahmy, Shaimaa A, Effat, Heba, Wahab, Abdel Hady Abdel,

Abstract


To date few reports have pointed out the role of circulating miRNAs in discriminating metastatic liver tumors from primary hepatocellular (HCC) tumors. Such discrimination will have significant therapeutic and prognostic implications. The purpose of this study was to evaluate the potential value of a panel of HCC-related circulating miRNAs (miR-142, miR-182, miR-200a, mir-210, miR-211, miR-302b, miR-324, miR-338, miR-340 and miR-1246) as noninvasive biomarkers for discriminating primary HCC from metastatic tumors in the liver.


Other data

Title Circulating MiR-210 and MiR-1246 as Potential Biomarkers for Differentiating Hepatocellular Carcinoma from Metastatic Tumors in the Liver
Authors Ahmed, Emad ; Fahmy, Shaimaa A; Effat, Heba; Wahab, Abdel Hady Abdel
Keywords HCC;biomarkers;circulating miRNAs;liver metastasis
Issue Date Apr-2019
Publisher DE GRUYTER POLAND SP ZOO
Journal Journal of medical biochemistry 
Volume 38
Issue 2
Start page 109
End page 117
ISSN 1452-8258
DOI 10.2478/jomb-2018-0010
PubMed ID 30867638
Scopus ID 2-s2.0-85056180138
Web of science ID WOS:000460757200001

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