Experimental study of modified voting algorithm for planted (l,d)-motif problem

Bahig, Hazem; Abbas, Mostafa M.; Bhery, Ashraf;

Abstract


We consider the planted (l,d)-motif search problem, which consists of finding a substring of length l that occurs in each s in a set of input sequences {s ,s } with at most d substitutions. In this paper, we study the effect of using Balla, Davila, and Rajasekaran strategy on voting algorithm practically. We call this technique, modified voting algorithm. We present an experimental study between original and modified voting algorithms on simulated data from (9,d) to (15,d). The comparison shows that the voting algorithm is faster than its modification in all instances except the instance (15,3). We also study the effect of increasing h, which is proposed by Balla, Davila, and Rajasekaran on the modified voting algorithm. From this study, we obtained the values of the number of sequences that make the running time of modified voting algorithm less than the voting algorithm and minimum. Finally, we analyze the experimental results and give some observations according to the relations: (1) l is fixed and d is variable. (2) l is variable and d is fixed. (3) l and d are variables. (4) (l,d) is challenging. © 2010 Springer Science+Business Media, LLC. i 1 t


Other data

Title Experimental study of modified voting algorithm for planted (l,d)-motif problem
Authors Bahig, Hazem ; Abbas, Mostafa M.; Bhery, Ashraf
Keywords Binding site;DNA motif;Exact algorithm;Planted (l,d)-motif;Voting algorithm
Issue Date 1-Dec-2010
Publisher SPRINGER-VERLAG BERLIN
Journal Advances in Experimental Medicine and Biology 
Start page 65
End page 73
ISBN 9781441959126
ISSN 00652598
DOI 10.1007/978-1-4419-5913-3_8
PubMed ID 20865487
Scopus ID 2-s2.0-79952198225
Web of science ID WOS:000283006100008

Recommend this item

Similar Items from Core Recommender Database

Google ScholarTM

Check

Citations 1 in pubmed
Citations 1 in scopus


Items in Ain Shams Scholar are protected by copyright, with all rights reserved, unless otherwise indicated.