Synthesis and fungicidal activity of new imidazoles from 2-(chloromethyl)-1H-benzimidazole

Hassan M. F. Madkour; Farag, A. A.; Ramses, S. Sh; Ibrahiem, N. A.A.;

Abstract


A series of substituted 2-thiomethylbenzimidazoles 2-4, 2-phenoxy-methylbenzimidazoles 5 and 2-aminomethylbenzimidazoles 6 and 7 were synthesized by reactions of 2-chloromethylbenzimidazole 1 with dithiocarbamate, pyrimidine-2-thiones, phenol derivatives, as well as primary aromatic and heterocyclic amines, respectively. Most of the synthesized compounds were screened for their antifungal activity against B. sinerea, F. solani, R. solani, and fungi. Some of the tested compounds showed 100% inhibition for the fungal growth at concentration ranges of 200-1000 ppm. Copyright © Taylor & Francis Group, LLC.


Other data

Title Synthesis and fungicidal activity of new imidazoles from 2-(chloromethyl)-1H-benzimidazole
Authors Hassan M. F. Madkour ; Farag, A. A.; Ramses, S. Sh; Ibrahiem, N. A.A.
Keywords ANTIBACTERIAL ACTIVITY;BENZIMIDAZOLES;DERIVATIVES;COMPLEXES;ZINC(II);AGENTS
Issue Date 1-Feb-2006
Publisher TAYLOR & FRANCIS LTD
Journal Phosphorus, Sulfur and Silicon and the Related Elements 
Volume 181
Issue 2
Start page 255
End page 265
ISSN 0308664X
DOI 10.1080/104265090970241
Scopus ID 2-s2.0-30344484827
Web of science ID WOS:000234923900003

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