A facile one-pot synthesis and antibacterial activity of aziridines and thiazines from 1,3-diarylprop-2-enones
Hassan M. F. Madkour; Salem, M. A.I.; Soliman, E. A.; Mahmoud, N. F.H.;
Abstract
The title compounds 1a,b as examples for acyclic alkenones were utilized for the synthesis of some heterocycles namely, thiazines 2a,b and 3a-d, pyrimidines 4a,b, aziridines 7a,b. The unexpected tribromides 8a,b, obtained from bromination of 1a,b, were readily used to afford the pyrazoles 9a,b and isoxazoles 10 a,b. Biological screening of some selective synthesised compounds was determined in vitro using Gram-negative and Gram-positive bacterial strains.
Other data
Title | A facile one-pot synthesis and antibacterial activity of aziridines and thiazines from 1,3-diarylprop-2-enones | Authors | Hassan M. F. Madkour ; Salem, M. A.I.; Soliman, E. A.; Mahmoud, N. F.H. | Issue Date | 1-Jan-2001 | Journal | Phosphorus, Sulfur and Silicon and the Related Elements | Volume | 170 | Issue | 1 | Start page | 15 | End page | 27 | ISSN | 10426507 | DOI | 10.1080/10426500108040582 | Scopus ID | 2-s2.0-0035541917 |
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