Synthesis and fungicidal activity of some new imidazoles from 2-(chloromethyl)-1H-benzimidazole

Hassan M. F. Madkour; Farag, A. A.; Ramses, S. Sh; Ibrahiem, N. A.A.;

Abstract


A SERIES of substituted 2-thiomethylbenzimidazoles 2-4, 2-phenoxymethylbenzimidazoles 5 and 2-aminomethylbenzimidazoles 6 and 7 were synthesized by reactions of 2-chloromethylbenzimidazole 1 with dithiocarbamate, pyrimidine-2-thiols, phenol derivatives as well as primay aromatic and heterocyclic amines, respectively. Most of the synthesized compounds were screened for their antifungal activity against Botrytis sinerea, Fusarium solani and Rhizoctonia solani fungi. Some of the tested compounds showed 100% inhibition for the fungal growth at concentration ranges from 200-1000 ppm.


Other data

Title Synthesis and fungicidal activity of some new imidazoles from 2-(chloromethyl)-1H-benzimidazole
Authors Hassan M. F. Madkour ; Farag, A. A.; Ramses, S. Sh; Ibrahiem, N. A.A.
Issue Date 1-Dec-2006
Journal Egyptian Journal of Chemistry 
ISSN 04492285
Scopus ID 2-s2.0-34047155076

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