X-ray, Microwave Assisted Synthesis and Spectral Data of 3-Amino-1-(3,5- dibromo-2-methoxy phenyl)-8-methoxy-1H-benzo[f]chromene-2-carbonitrile

Abstract

A convenient and efficient method using Microwave assisted synthesis of 3-amino-1-(3,5-di-bromo-2-methoxyphenyl)-8-methoxy-1H-benzo[f ]chromene-2-carbonitrile 5, via reaction of 6-methoxy-2-naphthol 1 with a mixture of 3,5-dibromo-2-methoxybenzaldehyde 2 and malononitrile 3 and also, by the reaction of 6-methoxy-2-naphthol 1 with 2-(3,5-dibromo-2-methoxybenzylidene)-malononitrile 4 in ethanolic piperidine solution was examined. Structure of the newly synthesized compound was confirmed on the on the basis of spectral data, IR, 1H NMR, 13C NMR, X-ray single crystal and MS. The molecular structure of 5, C22H16Br2N2O3, was crystallized in the Monoclinic, P 21/c, a = 9 1205 5 Å, b = 21 7827 14 Å, c = 10 6846 6 Å, = 107 620 2 , V = 2023 1 2 Å3, Z = 4.