Use of disubstituted thiosemicarbazide in synthesis of new derivatives of 1,3,4-thiadiazole, 1,2,4-triazole and pyrazole with their antimicrobial evaluation
Magdy M. Hemdan; Heba Kamal Abd El-Mawgoud;
Abstract
New derivatives of 1,3,4-thiadiazole, 1,2,4-triazole and pyrazole were obtained by cyclisation of the corresponding disubstituted thiosemicarbazide derivative. The newly synthesised derivatives were obtained in good yields and their structures were elucidated by spectral data and elemental analyses. The antimicrobial activity of some of the synthesised compounds is tested.
Other data
Title | Use of disubstituted thiosemicarbazide in synthesis of new derivatives of 1,3,4-thiadiazole, 1,2,4-triazole and pyrazole with their antimicrobial evaluation | Authors | Magdy M. Hemdan; Heba Kamal Abd El-Mawgoud | Keywords | 2-furoyl isothiocyanate;thiosemicarbazide;1,2,4-triazole;1,3,4-thiodiazole;2-cyanoacetohydrazide | Issue Date | Jun-2016 | Publisher | SAGE Publisher | Journal | Journal of Chemical Research | Volume | 40 | Issue | 6 | Start page | 345 | End page | 350 | DOI | 10.3184/174751916X14622845946035 |
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