Pegvisomant-primed growth hormone (GH) stimulation test is useful in identifying true GH deficient children

Radetti, Giorgio; Khalaf, Randa; Meazza, Cristina; Pagani, Sara; mohamed, elkholy; Albertini, Riccardo; De Stefano, Anna Maria; Navarra, Antonella; De Silvestri, Annalisa; Bozzola, Mauro; Elsedfy, Heba H;

Abstract


Provocative stimulation tests for growth hormone (GH) assessment have poor reproducibility and can often elicit false positive results in normal children. The aim of our study was to confirm the capability of pegvisomant as an enhancer of GH secretion in unmasking false-positive results in short children (height <-2.0 standard deviation score, SDS) undergoing GH testing.


Other data

Title Pegvisomant-primed growth hormone (GH) stimulation test is useful in identifying true GH deficient children
Authors Radetti, Giorgio; Khalaf, Randa; Meazza, Cristina; Pagani, Sara; mohamed, elkholy ; Albertini, Riccardo; De Stefano, Anna Maria; Navarra, Antonella; De Silvestri, Annalisa; Bozzola, Mauro; Elsedfy, Heba H 
Keywords GH | GH stimulation tests | GHD | Pegvisomant
Issue Date Jul-2017
Journal Hormones (Athens, Greece) 
ISSN 11093099
DOI 10.14310/horm.2002.1748
PubMed ID 29278515
Scopus ID 2-s2.0-85039746813

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