Growth hormone/IGF-I axis and growth hormone receptor mutations in idiopathic short stature

mohamed, elkholy; Mella, P; Buzi, F; Meazza, C; Zahra, S; Rashad, M.M.; Elsedfy, H.;

Abstract


It was hypothesized that some children with idiopathic short stature (ISS) may have partial insensitivity to growth hormone (GH). In this study analysis of the GH/IGF-I axis as well as GH receptor (GHR) gene was done in children with ISS to determine the possible underlying factor(s) to their short stature.


Other data

Title Growth hormone/IGF-I axis and growth hormone receptor mutations in idiopathic short stature
Authors mohamed, elkholy ; Mella, P; Buzi, F; Meazza, C; Zahra, S; Rashad, M.M.; Elsedfy, H. 
Keywords Growth hormone;Growth hormone-binding protein;Idiopathic short stature;IGF-I generation test;Receptor mutations growth hormone
Issue Date 1-Nov-2011
Journal Hormone research in paediatrics 
Volume 76
Issue 5
Start page 300
End page 306
ISSN 16632818
DOI 10.1159/000330191
PubMed ID 21846964
Scopus ID 2-s2.0-82455164214

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Citations 4 in pubmed
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