Chitosan and Solid Lipid Nanoparticles Enhance The Efficiency of Alpha-Lipoic Acid Against Experimental Neurotoxicity
Metwaly, Heba H; Fathy, Shadia A; Abdel Moneim, Mehrevan M; Emam, Manal A; Soliman, Ahmed; El-Naggar, Mehrez E; Omara, Enayat A; El-Bana, Mona A;
Abstract
α-LA can attenuate neurotoxicity induced by AlCl3 attributed to its anti-inflammatory, antioxidant and anti-apoptotic activities in addition to the effectiveness of the encapsulation technique that can increase efficiency and stability of α-LA. Moreover, α-LA-SLNPs is more efficient than α-LA-CsNPs.
Other data
| Title | Chitosan and Solid Lipid Nanoparticles Enhance The Efficiency of Alpha-Lipoic Acid Against Experimental Neurotoxicity | Authors | Metwaly, Heba H; Fathy, Shadia A; Abdel Moneim, Mehrevan M; Emam, Manal A; Soliman, Ahmed ; El-Naggar, Mehrez E; Omara, Enayat A; El-Bana, Mona A | Keywords | AlCl3;Chitosan Nanoparticles;Lipoic Acid;Neurotoxicity;Solid lipid Nanoparticles | Issue Date | 26-Oct-2021 | Journal | Toxicology Mechanisms and Methods | ISSN | 1537-6516 1537-6524 |
DOI | 10.1080/15376516.2021.1998275 | PubMed ID | 34697995 |
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