Synthetic Utility of Enaminonitrile Moiety in Heterocyclic Synthesis
Hassan M. F. Madkour; Aflf, A. A.B.; Elsayed, G. A.; Salem, M. S.;
Abstract
2-Amino-7-hydroxy-4-(3,4-dimethoxyphenyl)-4H-chromene-3-carbonitrile has been synthesized and utilized to construct a variety of new heterocyclic systems such as chromenopyrimidines, chromeno-oxazinone, chromenotriazolopyrimidinethiones, oxopyrazole derivative, chromenotetrazolopyrimidine via reactions with phenyl isothiocyanate, hydrazine hydrate in ethanol at room and refluxing temperatures, formamide and carbon disulfide in ethanolic potassium hydroxide and pyridine respectively. Some of the synthesized compounds have been found potent as antifungal and antibacterial. © 2006 Bulgarian Academy of Sciences, Union of Chemists in Bulgaria.
Other data
Title | Synthetic Utility of Enaminonitrile Moiety in Heterocyclic Synthesis | Authors | Hassan M. F. Madkour ; Aflf, A. A.B.; Elsayed, G. A.; Salem, M. S. | Keywords | 4H-chromene;Antimicrobial activity;Chromenopyrimidine;Chromenotetrazolopyrimidine;Enaminonitrile | Issue Date | 1-Dec-2008 | Journal | Bulgarian Chemical Communications | ISSN | 08619808 | DOI | https://api.elsevier.com/content/abstract/scopus_id/61549141459 | Scopus ID | 2-s2.0-61549141459 |
Recommend this item
Similar Items from Core Recommender Database
Items in Ain Shams Scholar are protected by copyright, with all rights reserved, unless otherwise indicated.