SYNTHESIS OF SOME NOVEL ANTIMICROBIAL AND ANTIOXIDANT AGENTS OF FUNCTIONALIZED PYRAZOLO[4 ',3 ':5,6]PYRANO[3,2-d]-[1,2] AZAPHOSPHOLES AND PYRAZOLO [4 ',3 ':5,6]PYRANO [2,3-d]-[1,3,2]DIAZAPHOSPHININES
Hassanin, NM; Ali, TE; Metwally El-Shaaer, Hafez; Abdel-Kariem, SM; El-Edfawy, SM; Abdel-Monem, WR;
Abstract
We have demonstrated facile synthetic approach for some novel functionalized pyrazolo[4',3':5,6]pyrano[3,2-d][1,2]azaphospholes and pyrazolo-[4',3':5,6]pyrano[2,3-d][1,3,2]diazaphosphinines via treatment of 6-amino-3-methyl-1,4-diphenyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile with some phosphorus halides. The structure of the products was characterized by elemental analysis and spectral tools. The antimicrobial and antioxidant activities of the products were also evaluated.
Other data
| Title | SYNTHESIS OF SOME NOVEL ANTIMICROBIAL AND ANTIOXIDANT AGENTS OF FUNCTIONALIZED PYRAZOLO[4 ',3 ':5,6]PYRANO[3,2-d]-[1,2] AZAPHOSPHOLES AND PYRAZOLO [4 ',3 ':5,6]PYRANO [2,3-d]-[1,3,2]DIAZAPHOSPHININES | Authors | Hassanin, NM; Ali, TE; Metwally El-Shaaer, Hafez ; Abdel-Kariem, SM; El-Edfawy, SM; Abdel-Monem, WR | Keywords | Antioxidant Agent;Pyrano[2,3-c]pyrazole;1,2-Azaphosphole;1,3,2-Diazaphosphinine;Antimicrobial Agent;BEARING;PHOSPHORUS;BIOLOGICAL-ACTIVITY | Issue Date | 2020 | Publisher | PERGAMON-ELSEVIER SCIENCE LTD | Journal | Heterocycles | ISSN | 0385-5414 | DOI | 10.3987/COM-20-14325 | Scopus ID | 2-s2.0-85096143867 | Web of science ID | WOS:000683753400010 |
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