Assessment of ultra-structure, viability and function of lipopolysaccharides-stimulated human dermal fibroblasts treated with chrysin and exosomes (in vitro study)

Hassan, Rabab; Sabry, Dina; Rabea, Amany A;

Abstract


Lipopolysaccharides (LPS) stimulate production of inflammatory cytokines. Chrysin is flavonoid beneficial for treatment of inflammatory conditions. Bone marrow mesenchymal stem cell (BM-MSC) exosomes have regenerative ability in different tissues.


Other data

Title Assessment of ultra-structure, viability and function of lipopolysaccharides-stimulated human dermal fibroblasts treated with chrysin and exosomes (in vitro study)
Authors Hassan, Rabab ; Sabry, Dina; Rabea, Amany A
Keywords BM-MSC exosomes;BM-MSCs, bone marrow mesenchymal stem cells;Chrysin;ELISA;ELISA, enzyme-linked immunosorbent assay;Fibroblast;HDFa, Human dermal fibroblasts-adult;HO-1, Heme oxygenase-1;IL-10, Interleukin-10;IL-1β, Interleukin-1β;LPS, lipopolysaccharides;MTT;Nrf2, Nuclear factor-erythroid 2-related factor 2;SD, standard deviation;p-value, probability value
Issue Date Jul-2022
Publisher ELSEVIER
Journal The Saudi dental journal 
Volume 34
Issue 5
Start page 346
End page 354
ISSN 1013-9052
DOI 10.1016/j.sdentj.2022.04.006
PubMed ID 35814848
Scopus ID 2-s2.0-85132655230
Web of science ID WOS:000821906200002

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