Tackling Microbial Resistance with Isatin-Decorated Thiazole Derivatives: Design, Synthesis, and in vitro Evaluation of Antimicrobial and Antibiofilm Activity
Kassab, Refaie M; Al-Hussain, Sami A; Elleboudy, Nooran; Albohy, Amgad; Zaki, Magdi E A; Abouzid, Khaled; Muhammad, Zeinab A;
Abstract
Antibiotic resistance is a global threat that has been increasing recently, especially with antibiotic overuse and misuse. The search for new antibiotics is becoming more and more indispensable.
Other data
| Title | Tackling Microbial Resistance with Isatin-Decorated Thiazole Derivatives: Design, Synthesis, and in vitro Evaluation of Antimicrobial and Antibiofilm Activity | Authors | Kassab, Refaie M; Al-Hussain, Sami A; Elleboudy, Nooran ; Albohy, Amgad; Zaki, Magdi E A; Abouzid, Khaled ; Muhammad, Zeinab A | Keywords | 5-bromoisatin;MRSA;Tyrosyl-tRNA synthetases (TyrRS) inhibitors;antibiofilm;antimicrobial;hydrazonoyl chlorides;molecular docking;thiazoles;thiosemicarbazone | Issue Date | 2022 | Publisher | DOVE MEDICAL PRESS LTD | Journal | Drug design, development and therapy | Volume | 16 | Start page | 2817 | End page | 2832 | ISSN | 1177-8881 | DOI | 10.2147/DDDT.S365909 | PubMed ID | 36046334 | Scopus ID | 2-s2.0-85136286760 | Web of science ID | WOS:000860559000001 |
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