Early Optical Coherence Tomography Angiography Changes among Children and Adolescents with Type 1 Diabetes; Relation to Fibroblast Growth Factor 21

Sherif, Eman M.; Matter, Randa M; Salah, Nouran; Eldin H Abozeid, Nour; Atif, Heba M; Tantawy, Nermien M;

Abstract


Current diagnostic and treatment modalities target late stages of diabetic retinopathy, when retinopathy has already been established. Novel and more sensitive strategies are needed. Optical coherence tomography angiography (OCTA) permits non-invasive visualization of retinal microcirculation. Fibroblast growth factor-21 (FGF21) plays an important role in glucose and lipid homeostasis. This study assesses early OCTA changes among children and adolescents with T1DM, compared to fundus photography and correlates them to diabetes-duration, glycemic control and FGF21; hence, determine their value in early detection of DR.


Other data

Title Early Optical Coherence Tomography Angiography Changes among Children and Adolescents with Type 1 Diabetes; Relation to Fibroblast Growth Factor 21
Authors Sherif, Eman M. ; Matter, Randa M ; Salah, Nouran ; Eldin H Abozeid, Nour; Atif, Heba M; Tantawy, Nermien M
Keywords FGF21;Optical Coherence Tomography Angiography;children;type 1 diabetes
Issue Date 9-Dec-2022
Journal Diabetes and Metabolic Syndrome: Clinical Research and Reviews 
ISSN 1520-7552
1520-7560
DOI 10.1002/dmrr.3598
PubMed ID 36494875

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