Phenotypic and genotypic characterization of linezolid resistance and the effect of antibiotic combinations on methicillin-resistant Staphylococcus aureus clinical isolates

AbdAlhafiz, Asmaa I; Elleboudy, Nooran; Aboshanab, Khaled; Aboulwafa, Mohammad M; Hassouna, Nadia A;

Abstract


Methicillin-Resistant Staphylococcus aureus (MRSA) causes life-threatening infections, with narrow therapeutic options including: vancomycin and linezolid. Accordingly, this study aimed to characterize phenotypically and genotypically, the most relevant means of linezolid resistance among some MRSA clinical isolates.


Other data

Title Phenotypic and genotypic characterization of linezolid resistance and the effect of antibiotic combinations on methicillin-resistant Staphylococcus aureus clinical isolates
Authors AbdAlhafiz, Asmaa I; Elleboudy, Nooran ; Aboshanab, Khaled ; Aboulwafa, Mohammad M ; Hassouna, Nadia A 
Keywords 23 S rRNA;Antibiotic combinations;Biofilm;Cfr(b) gene;Linezolid;MRSA;Mutations;Ribosomal genes;Synergism
Issue Date 3-Apr-2023
Journal Annals of clinical microbiology and antimicrobials 
ISSN 1476-0711
DOI 10.1186/s12941-023-00574-2
PubMed ID 37013561
Scopus ID 2-s2.0-85151656530

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