Impact of lipophilic vs hydrophilic statins on the clinical outcome and biomarkers of remodelling in heart failure patients: A prospective comparative randomized study
El Said, Nouran Omar; El Wakeel, Lamia Mohamed; Khorshid, Hazem; Darweesh, Ebtissam Abdel Ghaffar; Ahmed, M. A.;
Abstract
There are insufficient direct comparative studies addressing the impact of the type of statin on their respective efficacy in heart failure (HF). The aim of the current study was to compare the effects of lipophilic (atorvastatin) vs hydrophilic (rosuvastatin) on left ventricular function, inflammatory and fibrosis biomarkers in patients with chronic HF.
Other data
| Title | Impact of lipophilic vs hydrophilic statins on the clinical outcome and biomarkers of remodelling in heart failure patients: A prospective comparative randomized study | Authors | El Said, Nouran Omar; El Wakeel, Lamia Mohamed; Khorshid, Hazem; Darweesh, Ebtissam Abdel Ghaffar; Ahmed, M. A. | Keywords | heart failure; hydrophilic; lipophilic; remodelling; soluble ST2; statin | Issue Date | Jul-2021 | Publisher | WILEY | Journal | British journal of clinical pharmacology | Volume | 87 | Issue | 7 | Start page | 2855 | End page | 2866 | ISSN | 0306-5251 | DOI | 10.1111/bcp.14695 | PubMed ID | 33294980 | Scopus ID | 2-s2.0-85099018851 | Web of science ID | WOS:000604246900001 |
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