Analysis of mRNA-miRNA-lncRNA differential expression in prediabetes/type 2 diabetes mellitus patients as potential players in insulin resistance
Ali, Hebatalla Said; Kamel, Marwa Mostafa; Agwa, Sara H A; Hakeem, Mohamed S Abdel; Meteini, Mahmoud Shawky El; Matboli, Marwa;
Abstract
Type 2 diabetes mellitus (T2DM) is a major global health concern. It usually develops gradually and is frequently preceded by undetectable pre-diabetes mellitus (pre-DM) stage. The purpose of this study was to identify a novel set of seven candidate genes associated with the pathogenesis of insulin resistance (IR) and pre-DM, followed by their experimental validation in patients' serum samples.
Other data
| Title | Analysis of mRNA-miRNA-lncRNA differential expression in prediabetes/type 2 diabetes mellitus patients as potential players in insulin resistance | Authors | Ali, Hebatalla Said; Kamel, Marwa Mostafa; Agwa, Sara H A; Hakeem, Mohamed S Abdel; Meteini, Mahmoud Shawky El ; Matboli, Marwa | Keywords | Bioinformatics;Biomarkers;Insulin resistance;Non-coding RNA;Pre-diabetes;Type 2 diabetes mellitus | Issue Date | 8-May-2023 | Journal | Frontiers in Endocrinology | ISSN | 1664-2392 | DOI | 10.3389/fendo.2023.1131171 | PubMed ID | 37223012 | Scopus ID | 2-s2.0-85159877806 |
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