Pomegranate juice and punicalagin-mediated chemoprevention of hepatocellular carcinogenesis via regulating miR-21 and NF-κB-p65 in a rat model
Hussein, Aya M; El-beih, Nadia; Swellam, Menha; El-Hussieny, Enas A;
Abstract
Hepatocellular carcinoma (HCC) is the most common neoplasm among primary liver malignancies, accounting for 70%-85% of total liver cancer cases worldwide. It is also the second-leading cause of cancer-related death worldwide. Recent research has investigated naturally occurring products high in polyphenolic compounds in the regression and prevention of HCC. This study investigated the chemoprevention effects of pomegranate juice (PJ) and punicalagin (PCG) against diethylnitrosamine (DENA)-induced hepatocarcinogenesis in male albino rats.
Other data
| Title | Pomegranate juice and punicalagin-mediated chemoprevention of hepatocellular carcinogenesis via regulating miR-21 and NF-κB-p65 in a rat model | Authors | Hussein, Aya M; El-beih, Nadia ; Swellam, Menha; El-Hussieny, Enas A | Keywords | Apoptosis;HCC;Hepatic antioxidants;NF-κB-p65;Pomegranate juice;Punicalagin;TNF-α;miR-21 | Issue Date | 2-Nov-2022 | Journal | Cancer cell international | ISSN | 1475-2867 | DOI | 10.1186/s12935-022-02759-9 | PubMed ID | 36324170 | Scopus ID | 2-s2.0-85141088920 |
Recommend this item
Similar Items from Core Recommender Database
Items in Ain Shams Scholar are protected by copyright, with all rights reserved, unless otherwise indicated.