Outcome Assessment of Closed Negative pressure wound therapy use to decrease Surgical Site Infection in Elective Paediatric Colorectal Procedures in Comparison with the Standard Wound Care

Abstract

Background: Surgical site infections (SSI) are the most common and costly of all hospital-acquired infections. Negative pressure wound therapy (NPWT) is a relatively new treatment option which considered in our study to decrease surgical nosocomial events in elective paediatric colorectal procedures in comparison with the standard wound care. Method: A randomized control study was conducted in paediatric surgery department. Lower statistical difference of infection frequency in NPWT group comparing to standard wound care group was revealed. Results: We enrolled 300 children who underwent a colorectal procedure. The study population was randomly allocated into two groups: Group A: standard wound care (n=150), Group B: negative pressure wound care (n=150). There was no statistical difference among the different group according to baseline characteristics, lab investigation and the surgical procedures. There was significant difference between the two groups according the frequency of infection (P value >0.001). Also, subgroup analysis regarding to the age group showed significant difference according to the frequency of the complication. Regarding hospitalization, there was statistical difference of the duration of hospitalization (P value >0.001). there was no statistical difference among the different group according to the frequency of infection, discharge and results of culture of the discharged infection. Conclusion: Our study concluded that NPWT use in the colorectal surgical procedure in paediatric has beneficial in the setting of decrease the incidence of SSI and the need for home nursing post-surgery and also decrease the duration of home nursing in those whom need it.