Correlation between the Serum Level of Ferritin and D-Dimer and the Severity of COVID-19 Infection

Abstract

ne most unforgettable pandemic is coronavirus 2019 (COVID 19) which is the most memorable pandemic of the twenty-first century. The diagnosis of COVID19 is based on purely clinical symptoms and real time reverse transcription polymerase chain reaction (RT-PCR) test. Serum ferritin and D-dimer tests play a major role in identifying the infections in the human body. The current study aimed at correlating the levels of serum Ferritin and D-Dimer to the severity of COVID-19 infection, it was a retrospective study done by retrieving data of 150 COVID-19 patients who were admitted at Ain-Shams University specialized hospital - Obour in the period from the 1st of April 2020 till the 31st of July 2020. It was found that there was a highly significant correlation between levels of serum Ferritin and D-Dimer and the severity of COVID-19 infection (P-value 0.000). There was a highly significant correlation between severity of COVID-19 infection and the primary outcome (mortality), need for ICU admission and mechanical ventilation (P-value 0.000) while it had no relation with the days of hospital stay (P-value 0.212).