The PRECISE-DAPT SCORE AS A PREDICTOR OF CONSTRAST INDUCED NEPHROPATHY IN ACUTE CORONARY SYNDROME PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTION

Abstract

This was a prospective observational cohort study conducted on 200 patients with Acute coronary syndrome (ACS), and undergoing percutaneous coronary intervention (PCI); to evaluate the predictive value of PRECISE DAPT score for the development of contrast induced nephropathy (CIN) in acute coronary syndrome patients undergoing PCI, and compare its predictive power to Mehran score. A total of 200 patients who have been diagnosed with Acute coronary syndrome, and undergoing PCI, patients were recruited from Ain Shams University Hospitals and enrolled in the study. The primary end-point was the development of CIN after PCI. CIN defined as an increase of > 25%, and/or > 0.5 mg/dl in serum creatinine at 48-72 hours after PCI when compared to baseline value. The predictive power of PRECISE-DAPT score was be tested, and the best cut-off value was determined. We compared the predictive power of PRECISE-DAPT score to Mehran risk score for the development of CIN.