“The Effect Of Titanium Dioxide Nanoparticles And Its Withdrawal On Submandibular Salivary Gland Of Albino Rats”

Abstract

Nano-based technology invaded many fields with extreme improvements such as in medicine, cosmetics, agriculture and food industry. Consequently, the human beings have been exposed more often to nanoparticles after their intrusion in our environment. One of the main food additives and world widely used is TiO2 nanoparticles that are found in candies, sweets and chewing gums. Their oral exposure is more likely occurring to the coming generations due to great use in many dietary products. Nano-TiO2 particles that enter the body via the gastrointestinal tract are absorbed and reach different body organs. These nanoparticles are progressively manufactured, therefore increased exposure can be expected, which has put TiO2 NPs under toxicological inspection. To investigate the toxic effect of titanium dioxide food additive nanoparticles and the possible recovery after withdrawal on the submandibular salivary gland of albino rats.