THE PRODUCTION, IMMOBILIZATION AND APPLICATION OF LACTIC ACID BACTERIA AS A PROBIOTIC

Abstract

Probiotic lactic acid bacterial strains must be chosen according to accurate selection criteria in order to survive the transition through gastrointestinal tract and preferably colonize the intestinal tract for a sufficiently long period to achieve the desired healthy effect. One of the most important properties of probiotics is protection against pathogens in the intestinal tract of the host. The role of antimicrobial compounds produced by probiotic strains as prophylactic agents against entric infections. The antimicrobial activity of starter cultures and probiotic bacteria has been attributed to the production of metabolites such as organic acids (lactic and acetic acid), hydrogen peroxide, ethanol, diacetyl, acetaldehyde, other low molecular mass compounds with antimicrobial activity and bacteriocins. The objective of this study was isolation, selection and identification of the most efficient lactic acid bacteria based on their safety assessment. Studies were focused on LAB characterization, immobilization and its antimicrobial effect against various pathogens as well as some application as antimutagenic and antitumor agents.