Blood Lipid Levels in Patients with Intracerebral Haemorrhage

Abstract

Background: Stroke is one of the leading causes of death and disability worldwide. Intracerebral hemorrhage (ICH), an important subtype of the stroke, is characterized by high mortality and morbidity rates. Compared with ischemic stroke, hemorrhagic stroke is associated with higher mortality rate and currently there is no curative treatment. Objective: To describe the lipid abnormality and its association with clinical characteristics of intracerebral haemorrhage Subjects and Methods: The patients were selected from inpatients in Neurology department at Ain Shams University Hospitals in the period from October 2020 to September 2021. The study included one hundred patients more than eighteen years old with primary spontaneous non traumatic intracerebral haemorrhage, documented by CT brain within 24 hours of symptoms onset. Results: We found 67% of patients were with low TGs (<150 mg/dl), 52% with low TC (<200mg/dl), 53% with low LDL (<100mg/dl) and 67% with low VLDL levels(<40mg/dl). We found a significant association between low TGs, TC and LDL levels and incidence of ICH, unlike HDL. Follow up by CT scan after one week was done among study group, and there were nine patients (9%) died during the follow up, while eighteen patients (18%) were complicated with hematoma expansion. And we found no relation between low lipid profile and outcome of ICH as regard hematoma expansion and mortality rates. Conclusion: We found highly statistically significant association between ICH and low TGs value. We found low TC and LDL levels were associated with increased risk of ICH. We found no significant association of HDL and risk of hemorrhagic stroke. We found no relation between low lipid profile and outcome of ICH as regard hematoma expansion and mortality rates.