Cord Blood levels of Brain-Derived Neurotrophic Factor (BDNF) In Full Term Neonates at Risk for Iron Deficiency

Abstract

Background Iron is a critical micronutrient for tissue oxygenation, cellular metabolism, energy generation, and the metabolism of toxins. Iron transfer from mother to fetus is a regulated process involving iron status in the maternal circulation, its transport across the placenta and subsequent transfer into the fetal circulation. Objective: To evaluate cord blood Hemoglobin (Hb) levels in neonates of mothers with iron deficiency anemia (IDA). Patients and Methods: This prospective case-control study was conducted at Ain Shams University Hospitals. It included 60 full terms newborn who were born at Obstetrics and Gynecology Hospital. An informed consent was taken from the mother or case giver before enrollment in the study. Results: In comparison between cases and controls as regard RBCS parameter, there was no significant difference between cases and controls regarding neonatal Hemoglobin and MCH, but there was significantly lower MCV in cases compared to controls. Conclusion: There was no relation between the maternal Hb deficient levels and neonatal Hb. The first sign of iron deficiency in neonates reflected in lower MCV in cases, but not reached to decrease Hb levels in neonates.