Transforming Growth Factor beta 2 (TGF-β2) in Breast-fed versus premature formula-fed preterm Neonates

Abstract

hypothesis that Breast Fed (BF) preterm neonates exhibit higher level of serum TGF-β2 and lower incidence of Feeding Intolerance (FI) compared to premature formula feed preterm neonates. We conducted a prospective, observational study in the period from May 2018 to October 2018 for 80 preterm neonates ≤ 36 wks at El-Demerdash Maternity Hospital NICU. It aimed to assess the occurrence of FI and NEC in preterm neonates and its relation to serum TGF-β2 in BF versus premature formula fed neonates. Eighty preterm neonates were enrolled. Inclusion criteria were GA ≤ 36 weeks. Exclusion criteria were the presence of any contraindication to feeding (e.g. GIT surgical condition), inborn error of metabolism, chromosomal abnormalities or congenital malformation. They allocated equally in 2 groups (BF group and premature formula fed group