Prognostic Value of Cardiac Troponin Release in Head Trauma Patients

Abstract

Traumatic brain injury (TBI) is defined as damage to the brain sustained after the application of external physical force that causes temporary or permanent functional or structural damage to the brain. TBI stands as a major cause of death among youth in industrialized societies. Brain injury can be mild, moderate, and severe. TBI biomarkers can also be used as a prognostic tool in the ED setting, in neurointensive care unit for the more severely injured patients or even in an out-of-hospital setting. For mTBI cases, similar biomarkers might predict the possible development of persistent post-concussive syndrome (PCS). Several protein biomarkers have shown some promise in this emerging area.