The Prognostic Value of Hypophosphatemia in Acute Exacerbation of Chronic Obstructive Pulmonary Disease (COPD)

Abstract

hosphorus (P) is an important electrolyte that plays a significant role in different physiological processes especially muscle contraction and adenosine triphosphate high energy bonds. Low phosphorus level in blood may increase the exacerbation of chronic obstructive pulmonary disease, need, and duration of mechanical ventilation. The aim of the study is to examine the prognostic effects of hypophosphatemia in COPD patients and evaluate the correlation between phosphorus levels and severity of attacks, need for mechanical ventilation, duration of The ICU stays and mortality. This study was performed on 72 patients with acute exacerbation of COPD admitted in chest department and respiratory ICU in Ain Shams University Hospital in the period between June 2019 & March 2020. Patients were classified into two groups according to admission serum phosphorus levels: Group 1 (normal phosphorus levels: 2.5 – 4.5 mg/dl) 36 patients