"Comparison of the Antibacterial Effect of Azadirachta indica {Neem) as A New Root Canal lrrigant for Primary Teeth versus Sodium Hypochlorite and Chlorhexidine" An In-Vitro Study

Abstract

ne of the most important reasons of endodontic treatment failure is the persistence or survival of microorganisms in the complex root canal system or periapical area; therefore, the success of endodontic treatment depends, to a great degree, on the elimination of microorganisms from the root canal system through mechanical instrumentation and chemical irrigation.[45]

Profound irrigation of the canals with antimicrobial solutions is an important step to decrease the number of microorganisms or eliminate them from the root canal system. E. faecalis has been reported in high prevalence in primary endodontic infections affecting children.[39]

The purpose of this study was to compare the antimicrobial effect of Azadirachta indica (Neem) as an intracanal irrigant with 2% CHX and 2.5% NaOCl when used as root canal irrigants in extracted primary teeth contaminated with E. faecalis bacteria.

Fifty extracted primary teeth were decoronated and only the roots were used in this study, randomly divided into four experimental groups, one positive control group and one negative control group as follows: CHX Group (I): consisted of 10 roots that were contaminated and irrigated with 2% CHX solution, Sodium Hypocloride Group (II): consisted of 10 roots that were contaminated and irrigated with Sodium Hypocloride,