The efficacy of oxytocin versus human chorionic gonadotrophin as a trigger for ovulation: A Randomized controlled trial

Abstract

nfertility is defined by the failure to achieve a clinical pregnancy after 12 months or more of regular unprotected sexual intercourse. The lack of ovulatory cycles may be considered as a major problem for women seeking pregnancy. This is reflected by the fact that about 20 percent of couples visiting a fertility clinic with an unfulfilled wish to conceive present with anovulation (Barthelmess and Naz, 2014). Ovulation induction involves taking medication to induce ovulation by encouraging eggs to develop in the ovaries and be released, increasing the chance of conception through timed intercourse Triggering of ovulation means taking medication to promote follicular rupture and release of ovum Several studies have explained the effect of many protocols on the ovulation and conception rates in ovulatory infertile women and hormone (LH) surge and maturation of the final stage of oocyte in these patients (Raju et al., 2013). Human chorionic gonadotropin (HCG) is the most common protocol that has been used in combination with clomiphene citrate in these women as an alteration to L.H for a long time. This method has been used as the standard approach for the induction of final stages of oocyte maturation (Yilmaz et al., 20016).