The accuracy of fetal liver volume measurements by three-dimensional ultrasound in the diagnosis of gestational diabetes mellitus during the second trimester

Abstract

This study was designed to evaluate the value of midtrimester VLF measurement by 3D ultrasound in the prediction of GDM. A total of 160 pregnant women with singleton pregnancy between 24 and 28 gestational weeks were included in the study. All the study participants were subjected to all needed workup to make sure they met the inclusion criteria of the current study then they were investigated by recent mean of screening for GDM by the confirmatory test(Gold standard) 2h 75g OGTT. The normal cut-off values for the test are: 92, 180 and 153 mg/dl (corresponding to fasting, 1h, and 2hs after glucose overload, respectively). Two changed values exceeding the thresholds are enough for GDM diagnosis. According to the results, all participants were allocated into GDM (+ve) and GDM (-ve) groups. The FLV measurement by 3D ultrasound was compared between each group. Whole of the collected data were statistically analyzed to compare all participants regarding FLV and GDM state (+/-) according to the inclusion and exclusion criteria.