Reproductive outcomes in Egyptian women following uterine septum resection

Abstract

Incomplete resorption of the mullerian duct during embryogenesis leads to mullerian anomalies that result in uterine defect which may alter the reproductive outcomes of the patients. Septate uterus is the most frequent congenital malformation of the female reproductive tract. It is a mullerian anomaly resulting from incomplete resorption of paramesonephric ducts during the eleventh week of fetal development. Its frequency is difficult to determine because of different classification methods. The frequency of septate uterus was estimated to be 5% among the general population. The anomaly accounts for 9% to 23% of genital malformations and 35% of uterine malformations. It is associated with various types of reproductive failure, including recurrent miscarriage, late abortion, and preterm delivery. No relationship has been shown between infertility and septate uterus. Uterine septum resection by a hysteroscopy approach has been proved to be beneficial with significant improvement in pregnancy rates post procedure as well as shorter operating and hospitalization periods, reduced risk of post-operative pelvic adhesions, low morbidity and an increased rate of vaginal delivery. The aim of the study was to evaluate the obstetric outcomes following hysteroscopic resection of uterine septum and its effects on live birth rates, rate of term pregnancies and fecundity in women who prior to