Assessment of Extent of Myocardial Injury in Patients Undergoing Transvenous Implantation of Permanent Pacemaker using Cardiac Troponin I (cTnI) as a Marker of Structural Heart Damage and it’s Relation to Different Sites of RV Implantation

Abstract

he term myocardial injury should be used when there is evidence of elevated cardiac troponin values (cTn) with at least one value above the 99th percentile upper reference limit (URL). The myocardial injury is considered acute if there is a rise and/or fall of cTn values. The cardiac troponin I (cTnI) is a part of the cardiac contractile apparatus, the troponin-tropomyosin complex. It is a very sensitive laboratory marker of myocardial cell necrosis and one of the gold standard measurements in detecting myocardial injury. Elevated cTnI levels maybe associated with a variety of clinical conditions like myocardial infarction, acute pulmonary edema, ventricular tachycardia, shock, acute renal impairment The aim of the study is to assess the extent of myocardial injury in patients undergoing trans-venous implantation of permanent pacemaker using cardiac troponin I (cTnI) as a marker of myocardial injury and it’s relation to different sites of RV pacing and number of trials of screwing the RV lead into the myocardium.