Optical Coherence Tomography Angiography in Micro Pulsed Laser in Treatment of Diabetic Macular Edema

Abstract

ubthreshold micro pulse yellow laser showed long-term efficacy in diffuse diabetic macular edema treatment in reducing central macular thickness and improving visual acuity. The level of HbA1c did not correlate significantly with the initial and final macular sensitivity, BCVA and CMT. The SMPLT is safe procedure, because no retinal damage was observed after laser treatment. Morphologic and visual function data reported in this study are adding new insights about safety of yellow MPL treatments in DME. Our study evaluated yellow 577-nm micro pulse laser in patients with DME. There was a statistically significant improvement in VA at follow-up visits, statistically significant decrease of the central macular thickness on OCT, and there was a statistically significant improvement in macular sensitivity at follow-up visits. Our study is one of a few studies to evaluate modifications on OCTA, after SMPL treatment in DME, documenting more pronounced changes in the DCP than in the SCP (decrease in FAZ area, number of MA). A significant decrease in the number of MA in the SCP and DCP occurred as early as 3 months after SMPL.