Evaluation of Health Related Quality of Life in Chronic HCV Egyptian Patients Treated with The New DAAs

Abstract

HCV is considered as a major public health problem in the world and particularly in Egypt due to the high prevalence of the HCV infection among the Egyptian population. We have found that beside the impact of the HCV infection on the physical component due to the bad consequences on the liver and the resultant liver cell failure; it had also a psychological impact on the quality of life. And in order to assess this affection we used two of the tools for assessing the HRQoL; one of them was a generic tool which is SF 36 V2 and the other was a newly translated version to Arabic of the disease specific questionnaire CLDQ which originally developed at 1999 by Youonssi ZM. The study was conducted on collaboration between the gastro-entrology and hepatology department in Agouza police hospital and Tropical department Ain shams university. The study was case control study included a total of 250 Patients divided in three groups of patients; • Group I included 50 HCV-negative subjects as a control. • Group II included 100 HCV patients before treatment and they are followed up after achieving the SVR12. • Group III included 100 HCV patients after treatment and achieving SVR.