Cardiac Affection in Pediatric CKD Patients in Relation to Hyperuricemia and its Treatment

Abstract

his study aimed to study the prevalence of hyperuricemia among CKD paediatric patients in stages 2,3,4 and its effect on cardiac indices, among children presented with CKD at Ain Shams university pediatrics hospital nephrology clinic during the period from December 2019 to February 2020. In addition, the affection of cardiac indices in CKD paediatric patients with hyperuricemia before and after the treatment with allopurinol for 6 months. The study was prospective cohort study which was conducted on 25 CKD pediatric patients in stages 2,3,4. The infants were recruited from Ain Shams University Pediatrics Hospital nephrology clinic during the period from December 2019 to February 2020. All infants were subjected to: History taking with special emphasis on the symptoms of kidney disease, any symptoms of nephrocalcinosis, history of any cardiac disease that might interfere with the Echocardiography finding in the study, history of any chronic diseases. Clinical examination laying stress on: complete physical examination for each participant before the study, anthropometric measurements before and after the 6 months therapy intervention.