Prevalence of Frailty in Elderly Patients with Renal Diseases

Abstract

Frailty can be defined as a clinical syndrome in which there is a state of dysregulation of energetics and multiple physiological systems when reaching a critical threshold, increase in an individual’s vulnerability to developing negative health-related events (including disability, hospitalizations, institutionalizations, and death) It can be due to accumulation of a number of unrelated diseases, impairments, and other health conditions in an individual or due to Age-associated declines in physiologic reserve and function across multi organ systems, leading to increased vulnerability for adverse health outcomes. Frailty is common in those with chronic kidney disease (CKD). The prevalence of frailty in the community-dwelling older adult population is reported to be 11%, whereas studies have reported a frailty prevalence of > 60% in dialysis-dependent CKD patients The aim is to determine the prevalence of frailty in patient with CKD and Hemodialysis patients and to study the effect of kidney diseases on the occurrence of frailty in elderly. We conducted a cross-sectional study to estimate the prevalence of frailty among elderly in patients with kidney disease.