Normal Morphological Variations Of Lymphocytes

Abstract

The normal adult human body contains on the order of a trillion (10)' Lymphocytes, most of which appear virtually identical (Daniel P. Stites, 1994). There are three different sizes of lymphocytes which are small (6-10 gm), large (14-20m) and intermediate (10• 14m) (Smetena et al., 1981). Atypical lymphocytes are large, irrigular cells, range in size from that of a large normal lymphocyte to greater than 30 m. Its nuclear and cytoplasmic mass are both increased, contributing to the overall size increase (Denise, 1992). The objectives of the study are : # 1. To elucidate the presence of atypical lymphocytes circulating in the peripheral blood of normal individuals, 2. To obtain the level of atypical lymphocytes in normal Egyptian individuals above which a disease is suspected and further investigations may be required. fie 3. To statistically correlate the atypical lymphocytes to other leucocytes in the peripheral blood.