RelationofIntestinalFloraDysbiosisandStressMarkerstoBodyCompositionandBehavior ofAutisticChildren

Abstract

hiscasecontrolstudywasconductedtodetectthelevelsofcortisolandoxytocininsalivaandLactobacillusandBifidobacteriainstoolofautisticchildren,andtocorrelateIntestinalfloradysbiosisandlevelsofstressmarkerswithbodycomposition,behaviorandlaboratoryvaluesamongautisticchildren. Sixty children were recruited. Thirty of them were autistic (26 males and 4 females), while thirty were normal children (12 male and 18 female). The age ranged from 5-8.5 yrs. ChildrenwithASDwerediagnosedaccordingtotheDiagnosticandStatisticalManualofMentalDisorders,5thEdition(DSM-5),ChildhoodAutismRatingScale(CARS),aswellastheGilliamAutismRatingScale(GARS).Anthropometricmeasurementsweremeasured.BMIwascalculated.BehavioralassessmentwasdoneusingVinelandAdaptiveBehaviorScaleandBehaviorProblemsInventory(BPI).SalivaryCortisolandOxytocinlevelsweremeasured.Quantitativereal-timePCRwasusedtodetermineLactobacillusandBifidobacteriaconcentrationsinthestoolsoftheenrolledsubjects.