SYNTHESIS OF SOME TETRAHYDROACRIDINE DERIVATIVES OF POSSIBLE PHARMACOLOGICAL ACTIVITY
Marwa El-Sayed Hassan El-Kady;
Abstract
In the present work, certain 9-substituted anilino (or phenoxy)-1,2,3,4- tetrahydroacridine derivatives were synthesized, hopping that the resultant compounds may exhibit favorable antimicrobial, antifungalanticholinesterase (cholinesterase inhibitor) and/or anticancer activities.
The thesis consists of the following parts:
I. Introduction :
This part includes a review on the various methods of synthesis and bi ological activities of 1,2,3,4-tetrahydroacridine and its derivatives.
I. Aim of the Present Investigation:
In this part the pharmacological basis (on which the synthesized compounds were chosen) is discussed.
HI. Theoretical Discussion of the Experimental Part:
This part deals with explanation of the reactions involved in the synthesis of both the key intermediates and the new final compounds as well as the elucidation of their structures spectroscopically. Schemes for the synthesis of the suggested compounds were given.
The thesis consists of the following parts:
I. Introduction :
This part includes a review on the various methods of synthesis and bi ological activities of 1,2,3,4-tetrahydroacridine and its derivatives.
I. Aim of the Present Investigation:
In this part the pharmacological basis (on which the synthesized compounds were chosen) is discussed.
HI. Theoretical Discussion of the Experimental Part:
This part deals with explanation of the reactions involved in the synthesis of both the key intermediates and the new final compounds as well as the elucidation of their structures spectroscopically. Schemes for the synthesis of the suggested compounds were given.
Other data
Title | SYNTHESIS OF SOME TETRAHYDROACRIDINE DERIVATIVES OF POSSIBLE PHARMACOLOGICAL ACTIVITY | Other Titles | تشييد بعض مشتقات التتراهيدرواكريدين المتوقع لها فاعلية فارماكولوجية | Authors | Marwa El-Sayed Hassan El-Kady | Issue Date | 1998 |
Attached Files
File | Size | Format | |
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B16280.pdf | 1.32 MB | Adobe PDF | View/Open |
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