Staphylococcus aureus skin colonization and its effect on children with atopic dermatitis

Abstract

This study aimed to evaluate the prevalence of S aureus skin colonization in children with AD and exploring the relation between staphylococcal enterotoxins to the clinical exacerbation of the disease . The study included 30 children with AD from Allergy and Immunology Unit, Children's Hospital of Ain Shams University Hospitals. Children with AD were divided into three clinical groups according to severity of the skin lesions:-

(1) Group (A) mild cases : Included 10 AD subjects (8males and 2 females) with mean age (20.10 ± 10.04 months) (2) Group (B) moderate cases: Included 14 AD subjects (5 males and 9 females) with mean age (18.50 ± 12.334 months) (3) Group (C) severe cases : Included 6 AD subjects (5 males and one female) with mean age (13.667 ± 12.228 months)

All AD children were subjected to complete history taking, clinical examination (including general and local examination of the skin lesions) and laboratory work up including:-

• Qualitative evaluation of S aureus organism.

• Quantitative evaluation of S aureus organism and toxins secreted. They were compared to thirty sex and age matched healthy controls.